|
|
Recent structures determined using the resources of the Macromolecular Crystallography Facility.
|
N. Yan, J.R. Huh, V. Schirf, B. Demeler, B.A. Hay, Y. Shi (2006) Structure and activation mechanism of the Drosophila initiator caspase Dronc. J Biol Chem 281, 8667-74. PDB entry 2FP3. |
|
M. Hu, L. Gu, M. Li, P.D. Jeffrey, W. Gu, Y. Shi (2006) Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway. PLoS Biol 4, e27. PDB entry 2F1W. |
|
F.Y. Li, P.D. Jeffrey, J.W. Yu, Y. Shi (2006) Crystal structure of a viral FLIP: insights into FLIP-mediated inhibition of death receptor signaling. J Biol Chem 281, 2960-8. PDB entry 2F1S. |
|
M. Hu, P. Li, L. Song, P.D. Jeffrey, T.A. Chenova, K.D. Wilkinson, R.E. Cohen, Y. Shi (2005) Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14. EMBO J 24, 3747-56. PDB entry 2AYN. |
|
N. Yan, J. Chai, E.S. Lee, L. Gu, Q. Liu, J. He, J.W. Wu, D. Kokel, H. Li, Q. Hao, D. Xue, Y. Shi (2005) Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans. Nature 437, 831-7. PDB entry 2A5Y. |
|
Y. Chao, E.N. Shiozaki, S.M. Srinivasula, D.J. Rigotti, R. Fairman R, Y. Shi (2005) Engineering a dimeric caspase-9: a re-evaluation of the induced proximity model for caspase activation. PLoS Biol 3, e183. PDB entry 2AR9. |
|
L. Feng, S. Zhou, L. Gu, D.A. Gell, J.P. Mackay, M.J. Weiss, A.J. Gow, Y. Shi (2005) Structure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem. Nature 435, 697-701. PDB entry 1Z8U. |
|
M.B. Neiditch, M.J. Federle, S.T. Miller, B.L. Bassler, F.M. Hughson (2005) Regulation of LuxPQ receptor activity by the quorum-sensing signal autoinducer-2. Mol Cell 18, 507-18. PDB entry 1ZHH. |
|
S.J. Riedl, W. Li, Y. Chao, R. Schwarzenbacher, Y. Shi (2005) Structure of the apoptotic protease-activating factor 1 bound to ADP. Nature 434, 926-33. PDB entry 1Z6T. |
Facility Manager: Phil Jeffrey, Schultz 417, 8-3978, pjeffrey@princeton.edu