Lakhina, V., Arey, R. N., Kaletsky, R., Kauffman, A., Stein, G., Keyes, W., Xu, D., and Murphy, C.T. (2015) "Genome-wide Functional Analysis of CREB/Long-Term Memory-Dependent Transcription Reveals Distinct Basal and Memory Gene Expression Programs." Neuron. Jan 21; 85(2): 330-345. [PDF]

Li, S., Stone, H.A., and Murphy, C.T. (2014) "A microfluidic device and automatic counting system for the study of C. elegans reproductive aging." Lab Chip. Dec 16;15(2):524-31. doi: 10.1039/c4lc01028k. [PubMed]

Ewald, C.Y., Landis, J.N., Abate, J.P., Murphy, C.T., and Blackwell, T.K. (2014) "Dauer-independent insulin/IGF-1 signaling implicates collagen remodelling in longevity." Nature. Dec 15: doi: 10.1038/nature14021. [Epub ahead of print] [PubMed]

Stein, G.M. and Murphy, C.T. (2014) "C. elegans positive olfactory associative memory is a molecularly conserved behavioral paradigm." Neurobiol Learn Mem. Nov;115:86-94. doi: 10.1016/j.nlm.2014.07.011. Epub 2014 Aug 7. [PubMed]

Fernandes de Abreu, D.A. et al. (2014) "An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology." PLoS Genet. Mar 27;10(3):e1004225. doi: 10.1371/journal.pgen.1004225. eCollection 2014 Mar. [PubMed]

Shi, C., Murphy, C.T. (2014) "Mating induces shrinking and death in Caenorhabditis mothers." Science. Jan 31; 343(6170): 536-40. [PubMed] [PDF]

Tepper RG, Murphy CT, Bussemaker HJ., (2014) DAF-16 and PQM-1: Partners in longevity. Aging (Albany NY) 6: 5-6 [Pubmed]

Murphy CT, Hu PJ. (2013) Insulin/insulin-like growth factor signaling in C. elegans. WormBook. Dec 26:1-43. doi: 10.1895 Wormbook.1.164.1. PMID: 24395814 Dec 26: 1-43. [Pubmed]

Caudy, A.A. et al. (2013) "A new system for comparative functional genomics of Saccharomyces yeasts." Genetics. Sep;195(1):275-87. doi: 10.1534/genetics.113.152918. Epub 2013 Jul 12. [PubMed]

Tepper RG(1), Ashraf J (1), Kaletsky R, Kleemann G, Murphy CT(2), Bussemaker HJ.(2) (Aug 1, 2013) PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity. Cell. 154(3):676-90. doi: 10.1016 /J.Cell. 2013.07.006. [PubMed]
(1)Co-first author
(2)Co-corresponding author

Blackstone C and Murphy CT (March 15, 2012). "Cell biology of disease and aging: a two-way street." Molecular Biology of the Cell, v 23, no 975 10.1091/mbc.E11-12-0985 [Molecular Biology of the Cell]

Stein GM and Murphy CT (2012) . "The intersection of aging, longevity pathways, and learning and memory in C. elegans." Front. Gene. 3:259. doi: 10.3389/fgene.2012. 0259 [Frontiers in Genetics and Aging]

Liu G, Rogers J, Murphy C.T., Rongo C. (2011) "EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan." EMBO J. 2011 Jun 14. doi: 10.1038/emboj.2011.195. [Epub ahead of print]
PMID:  21673654  [PubMed - as supplied by publisher] [PubMed]

Rizki, G., Iwata, T.N., Li, J., Riedel, C.G., Picard, C.L., Jan, M., Murphy, C.T., and Lee, S.S. (2011) "The Evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO." PLoS Genetics, 2011 Sep;7(9):e1002235. Epub 2011 Sep 1. [PubMed]

Luo S., and Murphy C.T. (2011). "C. elegans Reproductive Aging: Regulation and Underlying Mechanisms."Genesis Feb;49(2):53-65.doi: 10.1002/dvg.20694. Epub 2011 Jan 2 [PubMed]

Kauffman A. L., Parsons L, Stein G.M., Wills A. A., Kaletsky R. L. and Murphy C. T. (2011). "C. elegans Positive Butanone Learning, Short-term, and Long-term Associative Memory Assays." J.Vis. Exp.49,doi: 10.3791/2490 [JoVE]

Luo S., Kleemann G.A., Ashraf J.M., Shaw W.M., and Murphy C.T. (2010). "TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance." Cell. 2010 Oct 15;143(2):299-312.
PMID: 20946987 [PubMed - indexed for MEDLINE] [PubMed]

Research Highlight: Cell Press, Nature News &Views, New York Times

Kauffman A.L., Ashraf J.M., Corces-Zimmerman M.R., Landis J.N. and Murphy C.T. (2010). "Insulin Signaling and Dietary Restriction Differentially Influence the Decline of Learning and Memory with Age." PLoS Biol 8(5): e1000372. doi:10.1371/journal.pbio.1000372 [PLOS] [PDF] [PubMed]

Research Highlight: Nature Reviews Neuroscience

Kaletsky, R. and Murphy, C.T. (2010). "The role of insulin/IGF-like signaling in C. elegans longevity and aging." Disease Models & Mechanisms (2010) [PubMed] [PDF]

Landis, J.N. and Murphy, C.T. (2010). "Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO." Dev Dyn. 2010 Feb 5. [Epub ahead of print] [PubMed] [PDF]

Luo, S., Shaw, W. M., Ashraf, J., Murphy, C. T. (2009).  "TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging." PLoS Genet. 2009 Dec. 5 (12):e1000789. Epub 2009 Dec 24. [PubMed] [PDF]

**Oliveira, R.P., **Abate. J.P., **Dilks, K., Landis J. and Ashraf, J. (**co-first authors), *Murphy, C.T., and *Blackwell K. T. (*co-corresponding authors) (2009) "Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf." Aging Cell. 2009 Jul 3. [Epub ahead of print] [PubMed] [PDF]

Chikina, M. D., Huttenhower, C., *Murphy, C. T., and *Troyanskaya, O. G. (*co-corresponding authors) (2009) "Global Prediction of Tissue-Specific Gene Expression and Context-Dependent Gene Networks in Caenorhabditis elegans" PLoS Comput Biol 5(6): e1000417. [PLOS] [PDF]

Kleeman, G. A. and Murphy, C. T. (2009) “The endocrine regulation of aging in Caenorhabditis elegans. Molecular and Cellular Endocrinology 299: 51-57. [PDF]

Murphy, C. T., Lee, S.J., and Kenyon, C. (2007) “Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans." PNAS. 104(48): 19046-50. [PDF]

Shaw, W.M., Luo, S., Landis, J., Ashraf, J., and Murphy, C. T. (2007) “The C. elegans TGF-ß Dauer Pathway Regulates Longevity via Insulin Signaling.” Current Biology, Oct 9;17(19):1634-45. [PubMed]   [PDF]

Murphy, C. T. (2006).  "The Search for DAF-16/FOXO Transcriptional Targets: Approaches and Discoveries."  Experimental Gerontology 2006 Oct;41(10):910-21. Epub 2006 Aug 24.   [PubMed]   [PDF]

Murphy, C. T. (2006).  "Using Whole-Genome Transcriptional Analyses to Discover Molecular Mechanisms of Aging."  Drug Discovery Today: Disease Mechanisms  3(1): 41-46.   [PDF]

Kenyon, C. and Murphy, C. T. (2006).  "Enrichment of regulatory motifs upstream of predicted DAF-16 targets."  Nature Genetics  38(4): 397-8.   [PubMed]   [PDF]

Murphy, C. T. (2005).  "A Review of Genes that Act Downstream of the DAF-16 FOXO transcription factor to influence the lifespan of C. elegans."   Research and Perspectives in Longevity,  Longevity and Frailty, Springer.   [PDF]

McCarroll, S. A., Murphy, C. T., et al. (2004).  "Comparing genomic expression patterns across species identifies shared transcriptional profile in aging."   Nature Genetics  36(2): 197-204.   [PubMed]   [PDF]

Murphy, C. T., McCarroll, S., Bargmann, C. I., Fraser, A., Kamath, R. S., Ahringer, J., Li, H., Kenyon, C. (2003).  "Genes that Act Downstream of DAF-16 to Influence the Lifespan of C. elegans."   Nature 424: 277-83.   [PubMed]   [PDF]

Hsu, A. L., Murphy, C. T., and Kenyon, C. (2003).  "Regulation of aging and age-related disease by DAF-16 and heat-shock factor."   Science 300: 1142-5.   [PubMed]   [PDF]

Murphy, C. T., Rock, R. S., and Spudich, J. A. (2001).  "A Myosin II Mutation Uncouples ATPase activity from Motility and Shortens Step Size."   Nature Cell Biology 3: 311-315.   [PubMed]   [PDF]

Murphy, C. T. and Spudich, J. A. (2000).  "Variable Surface Loops and Myosin Activity: Accessories to a Motor."   J. Mus. Res. Cell Mot. 21: 139-151.   [PubMed]   [PDF]

Murphy, C. T. and Spudich, J. A. (1999).  "The Sequence of the Myosin 50-20K Loop Affects Myosin’s Affinity for Actin throughout the Actin-Myosin ATPase Cycle and Its Maximum ATPase Activity."   Biochemistry 38(12): 3785-3792.   [PubMed]   [PDF]

Murphy, C. T. and Spudich, J. A. (1998).  "Dictyostelium Myosin 25-50K Loop Substitutions Specifically Affect ADP Release Rates."   Biochemistry 37(19): 6738-6744.   [PubMed]   [PDF]