Publications Malaria Research   15. Lindner SE, De Silva EK, Keck JL, Llinás M. "Structural determinants of DNA binding by a P. falciparum ApiAP2 transcriptional regulator." Journal of Molecular Biology. 2009 In Press, Accepted Manuscript, Available online 10 November 2009. 14. Howitt CA, Wilinski D, Llinás M, Templeton TJ, Dzikowski R, Deitsch KW. "Clonally variant gene families in P. falciparum share a common activation factor." Mol Microbiol. 2009 Aug 24 epub ahead of print. 13. Zawada RJ, Kwan P, Olszewski KL, Llinás M, Huang SG. "Quantitative determination of urea concentrations in cell culture medium." Biochem Cell Biol. 2009 Jun;87(3):541-4. 12. Olszewski KL, Morrisey JM, Wilinski D, Burns JM, Vaidya AB, Rabinowitz JD, Llinás M. "Host-Parasite Interactions Revealed by Plasmodium falciparum Metabolomics" Cell Host Microbe. 2009 Feb 19; 5(2), pp. 191-199. 11. van Brummelen AC, Olszewski KL, Wilinski D, Llinás M, Louw AI, Birkholtz LM. "Co-inhibition of Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome, proteome and metabolome analyses." J Biol Chem. 2009 Feb 13;284(7), pp. 4635-46. 10. Llinás M., Deitsch KW., Voss TS. "Plasmodium gene regulation: far more to factor in." Trends Parasitol. 2008 Dec;24(12), pp. 551-6. 9. Tamez PA., Bhattacharjee S., van Ooij C., Hiller NL., Llinás M., Balu B., Adams JH., Haldar K. "An erythrocyte vesicle protein exported by the malaria parasite promotes tubovesicular lipid import from the host cell surface" PLoS Pathog. 2008 Aug 8;4(8):e1000118. 8. De Silva EK., Gehrke AR., Olszewski K., León I, Chahal JS., Bulyk ML., Llinás M. "Specific DNA-binding by Apicomplexan AP2 transcription factors". Proc Natl Acad Sci USA. 2008 Jun 17;105(24), pp. 8393-8.(See feature in Nature Reviews Microbiology) 7. Birkholtz L., van Brummelen AC., Clark K., Niemand J., Marechal E., Llinás M., Louw AI. "Exploring functional genomics for drug target and therapeutics discovery in Plasmodia" Acta Trop. 2008 Feb;105(2), pp. 113-23. 6. Hu G., Llinás M., Li J., Preiser PR., Bozdech Z. "Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy" BMC Bioinformatics. 2007 Sep 19;8:350. 5. Deitsch K., Duraisingh M., Dzikowski R., Gunasekera A., Khan S., Le Roch K., Llinás M., Mair G., McGovern V., Roos D., Shock J., Sims J., Wiegand R., Winzeler E. "Mechanisms of Gene Regulation in Plasmodium" Am J Trop Med Hyg. 2007 Aug;77(2), pp. 201-8. 4. Llinás M., Bozdech Z., Wong ED., Adai, AT., DeRisi JL. “Comparative whole genome transcriptome analysis of three Plasmodium falciparum strains” Nucleic Acids Res. 2006 Feb 21;34(4), pp. 1166-73. 3. Llinás, M. and del Portillo HA. “Mining the malaria transcriptome” Trends Parasitol. 2005 Aug;21(8), pp. 350-2. 2. Llinás, M. and DeRisi JL. “Pernicious plans revealed: Plasmodium falciparum genome wide expression analysis” Curr Opin Microbiol. 2004 Aug;7(4), pp. 382-7. 1. Llinás M. and Bozdech Z., Pulliam BL., Wong ED., Zhu J., DeRisi JL. “The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum” PLoS Biol. 2003 Dec;3(12):e426. Protein Folding, Stability, & Structure   5. Cellitti J., Llinás M., Echols N., Shank E. A. Gillespie B., Kwon E., Crowder S. M., Dahlquist F. W., Alber T., Marqusee S. "Exploring subdomain cooperativity in T4 lysozyme I: structural and energetic studies of a circular permutant and protein fragment"  Protein Sci. 2007 May;16(5):842-51. Epub 2007 Mar 30. 4. Llinás M., Gillespie B., Dahlquist FW., Marqusee S. "The energetics of T4 lysozyme reveal a hierarchy of conformations" Nat Struct Biol. 1999 Nov;6(11):1072-8. 3. Liu H., Farr-Jones S., Ulyanov NB., Llinás M., Marqusee S., Groth D., Cohen FE., Prusiner SB., James TL. “Solution structure of Syrian hamster prion protein rPrP (90-231)”Biochemistry. 1999 Apr 27;38(17):5362-77. 2. Llinás M. and Marqusee S. "Subdomain interactions as a determinant in the folding and stability of T4 lysozyme" Protein Sci. 1998 Jan;7(1):96-104. 1. Kohnert U., Wozny M., Llinás M., Roos A., Fischer S. "Active site labeling with dansyl-glutamyl-glycyl-arginyl chloromethyl ketone demonstrates the full activity of the refolded and purified tissue-type plasminogen activator variant BM 06.022" Appl Biochem Biotechnol. 1995 Nov;55(2):157-66. Other   Galgoczy DJ., Cassidy-Stone A., Llinás M., O'Rourke SM., Herskowitz I., DeRisi JL., Johnson AD. “Genomic dissection of the cell-type-specification circuit in Saccharomyces cerevisiae” Proc Natl Acad Sci U S A. 2004 Dec 28;101(52):18069-74.

246 Carl Icahn Lab Washington Road Princeton, NJ 08544
(609) 258-9391 office (609) 258-9496 laboratory (609) 258-3565 fax
manuel at genomics.princeton.edu
Last updated: August 11, 2008
Daniel Wilinski: Webmaster