Gavis Lab

Selected Publications

Xu X, Brechbiel JL, Gavis ER. Dynein-Dependent Transport of nanos RNA in Drosophila Sensory Neurons Requires Rumpelstiltskin and the Germ Plasm Organizer Oskar. J Neurosci. 2013 Sep 11;33(37):14791-800.

Olesnicky EC, Bhogal B, Gavis ER. (2012) Combinatorial use of translational co-factors for cell type-specific regulation during neuronal morphogenesis in Drosophila. Dev Biol. 365: 208-218.

Sinsimer KS, Jain RA, Chatterjee S, Gavis ER. (2011) A late phase of germ plasm accumulation during Drosophila oogenesis requires Lost and Rumpelstiltskin. Development. 138: 3431-3440.

Andrews S, Snowflack DR, Clark IE, Gavis ER. (2011) Multiple mechanisms collaborate to repress nanos translation in the Drosophila ovary and embryo. RNA. 17: 967-977.

Lerit DA, Gavis ER. (2011) Transport of germ plasm on astral microtubules directs germ cell development in Drosophila. Curr Biol. 21: 439-448.

Becalska AN, Kim YR, Belletier NG, Lerit DA, Sinsimer KS, Gavis ER. (2011) Aubergine is a component of a nanos mRNA localization complex. Dev Biol. 349: 46-52.

Becalska AN, Gavis ER. (2010) Bazooka regulates microtubule organization and spatial restriction of germ plasm assembly in the Drosophila oocyte. Dev Biol. 340: 528-538.

Becalska, A.N. and Gavis, E.R. (2009) Lighting up mRNA localization in Drosophila oogenesis. Development 136, 2493-2503.

Menon, K., Andrews, S., Murthy, M., Gavis, E.R. and Zinn, K. (2009) The translational repressors Nanos and Pumilio have divergent effects on presynaptic terminal growth and postsynaptic glutamate receptor subunit composition. J. Neurosci. 29, 5558-5572.

Kalifa, Y., Armenti, S.T., and Gavis, E.R. (2009) Glorund interactions in the regulation of gurken and oskar mRNAs. Dev. Biol. 326, 68-74.

Weil, T.T., Parton, R., Davis, I., and Gavis, E.R. (2008) Changes in bicoid mRNA anchoring highlight conserved mechanisms during the oocyte-to-embryo transition. Curr. Biol. 18, 1055-1061.

Brechbiel, J.L. and Gavis, E.R. (2008) Spatial regulation of nanos activity is required for its function in dendrite morphogenesis. Curr. Biol. 18, 745-750.

Jain, R.A. and Gavis, E.R. (2008) The Drosophila hnRNP M homolog, Rumpelstiltskin, regulates nanos mRNA localization. Development 135, 973-982.

Gavis, E.R., Chatterjee, S., Ford, N.R., and Wolff, L.J. (2008) Dispensability of nanos mRNAlocalization for abdominal patterning but not for germ cell development. Mech. Dev. 125, 81-90.

Jaramillo, A.M., Weil, T.T., Goodhouse, J., Gavis, E.R., and Schüpbach, T. (2008)  The dynamics of fluorescently labeled endogenous gurken mRNA in Drosophila. J. Cell Sci. 121, 887-894.

Gavis, E.R., Singer, R.H., and Hüttelmaier, S. (2007).  Localized translation through messenger RNA localization.  In Translational Control, J.W.B, Hershey, M.B. Mathews, and N. Sonenberg, eds (Cold Spring Harbor, NY: Cold Spring Harbor Laborator Press). pp. 687-717.

Weil, T.T., Forrest, K.M., and Gavis, E.R. (2006). Localization of bicoid mRNA in late oocytes is maintained by continual active transport. Dev Cell 11, 251-262.

Kalifa, Y., Huang, T., Rosen, L.N., Chatterjee, S., and Gavis, E.R. (2006). Glorund, a Drosophila hnRNP F/H homolog, is an ovarian repressor of nanos translation. Dev. Cell 10, 291-301.

Duchow, H.K., Brechbiel, J.L., Chatterjee, S., and Gavis, E.R. (2005). The nanos translational control element represses translation in somatic cells by a Beared box-like motif. Dev. Biol. 282, 207-217.

Forrest, K.M., Clark, I.E., Jain, R.A., and Gavis, E.R. (2004). Temporal complexity within a translational control element in the nanos mRNA. Development 131, 5753-5761.

Clark, I., Dobi, K., Duchow, H., Vlasak, A. and Gavis, E.R. (2002). A common translational control mechanism functions in axial patterning and endocrine signalling in Drosophila. Development 129, 3325-3334.

Bergsten, S.E., Huang, T., Chatterjee, S., and Gavis, E.R. (2001). Recognition and long range interactions of a minimal RNA localization signal element. Development 128, 427-435.

Clark, I., Wyckoff, D., and Gavis, E.R. (2000). Synthesis of the posterior determinant Nanos is spatially restricted by a novel cotranslational regulatory mechanism. Curr. Biol. 10, 1311-1314.

Bergsten, S.E. and Gavis, E.R. (1999). Role for mRNA localization in translational activation but not spatial restriction of nanos RNA. Development 126, 659-669.

Crucs, S., Chatterjee, S., and Gavis, E.R. (2000). Overlapping but distinct RNA elements control repression and activation of nanos translation. Mol. Cell 5, 457-467.

Gavis, E.R., Lunsford, L., Bergsten, S.E., Lehmann, R. (1996). A conserved 90 nucleotide element mediates translational repression of nanos RNA. Development 122, 2791-2800.