Lu X, Wang Q, Hu G, Van Poznak C, Fleischer M, Reiss M, Massagué J, and Kang Y. (2009) ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. Genes & Development, 23:1882-1894.

Korpal M, Yan J, Lu X, Xu S, Lerit D, and Kang Y. (2009) Imaging TGFb signaling dynamics and therapeutic response in breast cancer bone metastasis. Nature Medicine, 15:960-6.

Lu X and Kang Y. (2009) Acquisition of dual metastasis organotropism to bone and lung through spontaneous fusion between MDA-MB-231 breast cacner cell variants. Proc Natl Acad Sci USA, 106:9385-90.

Hu G, Chong RA*, Yang Q*, Wei Y, Blanco MA, Li F, Reiss M, Au J S.-L, Haffty B, and Kang Y. (2009) MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of breast cancer. Cancer Cell, 15(1):9-20. (Cover Article)

Korpal M and Kang Y. (2008) The emerging role of the miR-200 family microRNAs in epithelial-mesenchymal transition and cancer metastasis. RNA Biology, 5:112-116.

Korpal M, Lee ES, Hu G, and Kang Y. (2008) The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J. Biol. Chem., 283:14910-4.

Zhu J, Jia X, Xiao G, Kang Y, Patridge C, and Qin L. (2007). EGF-like ligands stimulate osteoclastogenesis by regulating expression of osteoclast regulatory factors in osteoblasts: implications in osteolytic bone metastases.  J. Biol.Chem., 282(37):26656-64.

Lu X and Kang Y (2007). Organotropism of breast cancer metastasis. J. Mammary Gland Biol. Neoplasia, 12(2-3):153-62.

Kang Y (2007). New tricks against an old foe: dissecting tissue tropism in breast cancer metastasis. Breast Disease, 26: 129-38.

Li F*, Tiede B*, Massagué J, Kang Y (2007). Beyond tumorigenesis: cancer stem cells in metastasis. Cell Res, 17:3-14. PDF

Kang Y (2006). Pro-metastasis function of TGFb mediated by the Smad pathway. J Cell Biochem 98: 1380-90. PDF

Gupta GP, Minn AJ, Kang Y, Siegel PM,  Serganova I, Cordon-Cardo C, Olshen AB, Gerald WL, and Massagué J.(2005). Identifying site-specific metastasis genes and functions. Cold Spring Harb Symp Quant Biol 70:149-58. PDF

Kang Y, He W, Tulley S, Gupta GP, Serganova I, Chen C, Manova-Todorava K, Blasberg R, Gerald WL, and Massagué J.(2005). Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway. Proc Natl Acad Sci USA 102: 13909-14. PDF

Minn AJ, Kang Y, Serganova I, Gupta GP, Giri DD, Doubrovin M, Ponomarev V, Gerald WL, Blasberg R, Massague J.(2005) Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. J Clin Invest 115: 44-55. PDF

Kang Y (2005). Functional genomic analysis of cancer metastasis: biologic insights and clinical implications. Expert Rev Mol Diagn 5: 385-95. PDF

Kang Y and Massague J (2004). Epithelial-mesenchymal transitions: twist in development and metastasis. Cell 118: 277-9. PDF

Bodem J, Kang Y and Flugel RM (2004). Comparative functional characterization of the feline foamy virus transactivator reveals its species specificity. Virology 318: 32-6. PDF

Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordon-Cardo C, Guise TA, Massague J.(2003). A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3: 537-49. PDF

Kang Y, Chen CR and Massague J (2003). A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells. Mol Cell 11: 915-26. PDF

Xu L, Kang Y, Col S and Massague J (2002). Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus. Mol Cell 10: 271-82. PDF

Wiegand HL, Coburn GA, Zeng Y, Kang Y, Bogerd HP, Cullen BR. (2002). Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes. Mol Cell Biol 22: 245-56. PDF

Ho DN, Coburn GA, Kang Y, Cullen BR and Georgiadis MM (2002). The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor. Proc Natl Acad Sci USA 99: 1888-93. PDF

Chen CR, Kang Y, Siegel PM and Massague J (2002). E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression. Cell 110: 19-32. PDF

Coburn GA, Wiegand HL, Kang Y, Ho DN, Georgiadis MM, Cullen BR.2001). Using viral species specificity to define a critical protein/RNA interaction surface. Genes Dev 15: 1194-205. PDF

Chen CR*, Kang Y* and Massague J (2001). Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program. Proc Natl Acad Sci USA 98: 992-9. PDF

Neufeld KL, Nix DA, Bogerd H, Kang Y, Beckerle MC,Cullen BR, and White RL. (2000). Adenomatous polyposis coli protein contains two nuclear export signals and shut tles between the nucleus and cytoplasm. Proc Natl Acad Sci USA 97: 12085-90. PDF

Kang Y, Bogerd HP and Cullen BR (2000). Analysis of cellular factors that mediate nuclear export of RNAs bearing the Mason-Pfizer monkey virus constitutive transport element. J Virol 74: 5863-71. PDF

Truant R*, Kang Y* and Cullen BR (1999). The human tap nuclear RNA export factor contains a novel transportin-dependent nuclear localization signal that lacks nuclear export signal function. J Biol Chem 274: 32167-71. PDF

Kang Y and Cullen BR (1999). The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences. Genes Dev 13: 1126-39. PDF

Kang Y, Bogerd HP, Yang J and Cullen BR (1999). Analysis of the RNA binding specificity of the human tap protein, a constitutive transport element-specific nuclear RNA export factor. Virology 262: 200-9. PDF

Kang Y and Cullen BR (1998). Derivation and functional characterization of a consensus DNA binding sequence for the tas transcriptional activator of simian foamy virus type 1. J Virol 72: 5502-9. PDF

Kang Y, Blair WS and Cullen BR (1998). Identification and functional characterization of a high-affinity Bel-1 DNA binding site located in the human foamy virus internal promoter. J Virol 72: 504-11.  PDF